Practical aspects of continuous intravenous treprostinil therapy.
نویسندگان
چکیده
CRITICALCARENURSE Vol 27, No. 2, APRIL 2007 41 Allison C. Widlitz was a physician assistant at the Columbia University College of Physicians and Surgeons Pulmonary Hypertension Center in New York, NY, when this article was written. She is currently Associate Director of Medical Affairs for Encysive Pharmaceuticals. Susanne McDevitt was a nurse practitioner at the University of Michigan Pulmonary Hypertension Center in Ann Arbor, Mich, when this article was written. She is currently a regional clinical specialist for United Therapeutics Corp. Ginger R. Ward was a nurse clinician at Duke University Pulmonary Hypertension Center in Durham, NC, when this article was written. She is currently a home infusion nurse for Accredo Therapeutics. Abby Krichman is program director at the Duke University Pulmonary Hypertension Center in Durham, NC.
منابع مشابه
Inhaled treprostinil and pulmonary arterial hypertension
Multiple conditions result in development of pulmonary hypertension. Pulmonary arterial hypertension (PAH) is the subclassification of pulmonary hypertension, in which known or unknown underlying conditions lead to similar intrinsic alterations in the pulmonary vasculature. PAH is a progressive condition characterized by restricted blood flow through the pulmonary circulation leading to poor su...
متن کاملHigh incidence of bloodstream infection due to gram-negative bacilli in patients with pulmonary hypertension receiving intravenous treprostinil.
INTRODUCTION An excessive risk for bacteremia has recently been reported in patients with pulmonary arterial hypertension (PAH) treated with intravenous treprostinil. We aimed to assess this association in a cohort of patients from a Spanish referral center. PATIENTS AND METHODS We performed a retrospective cohort study that included 55 patients diagnosed with PAH who received a continuous in...
متن کاملDose proportionality of treprostinil sodium administered by continuous subcutaneous and intravenous infusion.
This study assessed the relationship between dose and plasma concentration following administration of treprostinil sodium infusion therapy in pulmonary arterial hypertension patients. This was a multicenter, open-label, multiple-cohort, steady-state, pharmacokinetic study in subjects with pulmonary arterial hypertension receiving treprostinil by continuous intravenous or subcutaneous infusion ...
متن کاملTransitioning from i.v. epoprostenol to subcutaneous treprostinil in pulmonary arterial hypertension.
OBJECTIVE Continuous i.v. epoprostenol (prostacyclin) therapy improves survival and quality of life in patients with pulmonary arterial hypertension (PAH). i.v. epoprostenol therapy may be limited by serious complications related to the need for an implanted central venous catheter, and its chemical instability and short half-life. Treprostinil is a longer-acting prostacyclin analog, chemically...
متن کاملTransitioning from parenteral treprostinil to inhaled treprostinil in patients with pulmonary arterial hypertension
Treprostinil is a potent prostacyclin vasodilator indicated for the treatment of pulmonary arterial hypertension (PAH, World Health Organization Group I). Previously, treprostinil was available only in subcutaneous (SC) or intravenous (IV) formulations. Availability of an inhaled formulation of treprostinil has provided clinicians with an alternative to continuous SC or IV treprostinil in appro...
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ورودعنوان ژورنال:
- Critical care nurse
دوره 27 2 شماره
صفحات -
تاریخ انتشار 2007